Congratulations to the 2021 Leading Edge Fellows!

2021 Leading Edge Fellows

Rachel Zwick

Epithelial tissue patterning and regeneration

Xiaoxue (Snow) Zhou

Signal transmission in the yeast mitotic exit network

Zara Weinberg

Decoding signaling to understand cellular behavior

Lexy von Diezmann

Regulation of DNA repair outcomes in meiosis

Meike van der Heijden 

Neural signals during dynamic cerebellar development

Jeannette Tenthorey

Evolution of antiviral defenses

Chelsey Spriggs

Host-pathogen interactions during viral entry

Delia Shelton

 Environmental Psychology Innovation Center (EPIC): solving grand challenges in environmental and human health 

Rachel Shahan

Single-cell insights into organ development

Mohini Sengupta

Neural circuits for motor control in the spinal cord

Rebeca San Martin

Microenvironment influence on the 3D genome of prostate cancer

Melissa Roth

Regulation and dynamics of photosynthesis and metabolism

Aleah Roberts

Molecular mechanisms of non-canonical B Cell Receptor endocytosis

Deepa Ramamurthy

Neural circuits for attentional selection in sensory cortex

Novalia Pishesha

Engineered nanobodies as immune modulators for autoimmunity and infectious diseases

Sarah Pfau

The molecular and cellular bases of blood-brain barrier heterogeneity

Nicole Perry-Hauser

The role of latrophillins in cell signaling and synapse formation

Andrea Moffitt 

Genomic methods for liquid biopsies in cancer

Alexandria Miller

Structure and function of a SARS-CoV-2 accessory protein

Molly Matty

Microbiome influences on animal behavior 

Romila Mascarenhas 

Vitamin B12 trafficking and disease

Anne Martin

Identifying how synapse coordination is achieved across a neural circuit

Maria Maldonado

Structure and function of respiratory complexes and supercomplexes

Prerna Malaney

Role of RNA-binding proteins in cancer

Theresa Loveless

Synthetic cells that record their own history

Jennifer Kong

Mechanisms of morphogen sensitivity underlying congenital heart defects

Stacey Kigar

Neuroimmunology of stress-induced behavioral changes

Tegan Horan

Regulation of crossover formation in meiosis

Shan He

Biogenesis of the eukaryotic CO2 concentrating organelle, the pyrenoid

Kathryn Gunn

Structure and mechanism of lipid metabolizing proteins

Lydia Grmai

Sex-biased regulation of steroid hormones in gonad development

Ana Gonzalez-Reiche

Molecular evolutionary dynamics of virus transmission and host-virus interactions

Lisa Eshun-Wilson

Mitochondrial quality control by diverse proteases

Julie Elie

The neuroethology of vocal communication in bats and songbirds

Andrea d'Aquino

Sustained delivery of GLP-1 receptor agonists for the treatment of diabetes

Jeeyun Chung

Spatiotemporal regulation of lipid metabolism

Jenna Christensen

Intracellular transport diversity in fungal and human cells

Sisi Chen

Probing the multicellular mechanisms of drug response in heterogeneous immune cell populations

Caroline Bartman

Developing new methods to measure in vivo tumor metabolism

Arianna Baggiolini

The developmental chromatin programs underlying oncogenic competence in melanoma

Sweta Agrawal

Neural circuits underlying proprioception and motor control

Alice Accorsi

Development and regeneration of complex sensory organs

2020 Leading Edge Fellows

Helen Yang

Descending control of walking in Drosophila

Postdoc
Harvard Medical School

Sissy Wamaitha

Human germ cell lineage emergence

Postdoc
UCLA

Claudia Vásquez

Physics of epithelial lumen stability 

Postdoc
Stanford University

Christina Towers

Autophagy dependence in cancer cells 

Assistant Professor
Salk Institute 

Valerie Tornini

Chromatin modifiers in vertebrate development

Postdoc
Yale University

He Tian

 Directed evolution of biosensors for imaging neural activity

Postdoc
Harvard University

Monique Smith

Social communication of pain and elucidating the neural circuits of empathy

Incoming Assistant Professor,
University of San Diego

Naima Sharaf

 Structure and function of the Neisseria meningitidis ABC methionine transporter system

Assistant Professor,
Stanford University

Dorian Rosen

Modulating cellular stress responses to improve outcomes in neurological disorders

Postdoc
Scripps

Lauren Rajakovich

Human gut microbial metabolism

Incoming Assistant Professor, University of Washington

Cameron Ogg

Neural circuits underlying behavioral flexibility

Postdoc
St. Jude

Elizabeth Lawrence

Microtubule dynamic instability in vitro

Postdoc
Vanderbilt University

Lindsay LaFave

Chromatin state in lung adenocarcinoma

Incoming Assistant Professor, Albert Einstein College of Medicine

Aga Kendrick

Regulation of microtubule-based cellular transport

Postdoc
UCSD

Jennifer Kan

Designing and engineering de novo protein functions

Postdoc
Caltech

Victoria Hung

Ribosome heterogeneity in gene regulation and cell fate


Postdoc
Stanford University

Erin Hisey

Neural circuits underlying learning and forgetting


Postdoc
McLean Hospital, Harvard Medical School

Zoë Hilbert

New modalities in host-microbe evolutionary conflicts


Postdoc
University of Utah

Liz Haynes

Imaging neural development across whole-embryo and single cell scales

Postdoc
University of Wisconsin-Madison

Farah Haque

Microtubule-based regulatory mechanisms underlying signaling

Postdoc
Massachusetts General Hospital

Liangliang Hao

Engineering precision diagnostics for cancer

Postdoc
MIT

Mae Guthman

Plasticity of hormone-sensitive neural circuits

Postdoc
Princeton University

Jessica Gray

Single cell insights into evolution and development

Postdoc
Harvard Medical School

Aleena Garner

Neural circuits in memory-sensory interplay

Postdoc
Friedrich Miescher Institute

Jaye Gardiner

Cancer-associated fibroblasts in pancreatic cancer

Postdoc
Fox Chase Cancer Center

Lam-Kiu Fong

Membrane protein function in Alzheimer's disease

Postdoc
UCSF

Clarissa Durie

Visualizing bacterial secretion systems


Incoming Assistant Professor, University of Missouri

Anne Draelos

Real-time analysis and stimulation of neuronal populations

Postdoc
Duke University

Xintong Dong

Defensins and Mrgprs in skin immunity and itch


Postdoc
Johns Hopkins


Allison Didychuk

 DNA packaging in herpesviruses


Incoming Assistant Professor,
Yale University

Danfeng Cai

Chromatin organization and transcription regulation


Assistant Professor
Johns Hopkins School of Public Health

Liz Boydston

Specialized organelles for host-parasite interactions


Postdoc
Whitehead Institute

Heike Blockus

Linking synaptic specificity to neuronal circuit function


Senior Scientist
Verge Genomics

Cecilia Blengini

Chromosome segregation during female meiosis in mammals

Postdoc
Rutgers University

N. Sumru Bayin

Neural stem cell diversity and age-dependent regenerative processes in the brain

Incoming Group Leader
Gurdon Institute, Cambridge University

Sarah Ackerman

Neuron-glia dynamics in circuit development, refinement, and behavior

Incoming Assistant Professor,
Washington University School of Medicine